Research Interests:
Dynamics of circadian rhythm, Dynamics of cardiac metabolism, Cell cycle control and biological signal transduction, Mechanisms of biochemical oscillations
Education:
M.S. 1997, Soochow University, China Major: Applied Mathematics
Ph.D. 2002, Shanghai University, China Major: Applied Mathematics
Experience:
Postdoctor in the Cardiovascular Research Laboratory at the University of California, Los Angeles, USA .
Joined the Center for Systems Biology at Soochow University, China . 2008
Publication (selected papers):
Yan J., Shi G., Zhang Z., Wu X., Liu Z., Xing L., Qu Z., Dong Z., Yang L.*, and Xu Y.* ( *Corresponding author: Yang L. or Xu Y.), An intensity ratio of interlocking loops determines circadian period length, Nucleic Acids Research (2014), Volume: 42 Issue: 16, Pages: 10278-87
Liu, Zhiwei; Huang, Moli; Wu, Xi; et al., PER1 Phosphorylation Specifies Feeding Rhythm in Mice, Cell Reports (2014), Volume: 7, Issue: 5, Pages: 1509-1520
Shi, G. et al,Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock, Proceedings of the National Academy of Sciences of the United States of America, 2013,110(12), pp 4750-4755
Yan, J., Ni, X., Yang, L.*, Robust Cell Size Checkpoint from Spatiotemporal Positive Feedback Loop in Fission Yeast, Biomed Research International, 2013
Feng S., Yan J., Liu Z., Yang L*., The Dynamical Mechanisms of the Cell Cycle Size Checkpoint, Chinese Physics Letters, 29(10), 2012/10.