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  • 天元讲堂(8.15)Personalized characterization of diseases using sample-specific networks
  • 浏览量:205 发布人:佚名 发布时间:2017-08-15 09:58:37
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    报告人:陈洛南 中国科学院上海生命科学研究院
    报告时间:2017.8.15 13:00-14:00
    报告地点:维格堂113

    报告摘要:Estimating a condition-specific network from a single sample is crucial to elucidating the molecular mechanisms of complex diseases at the system level. I will introduce a novel statistical method, i.e. a sample-specific network (SSN) method, which allows us to construct individual-specific networks based on molecular expressions of a single sample. Using this method, we can characterize various human diseases at a network level. In particular, such SSNs can lead to the identification of individual-specific disease modules as well as driver genes, even without gene sequencing information.
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